Correct storage of botulinum toxin products is critical for maintaining potency and ensuring patient safety. Improper storage can reduce efficacy and compromise product integrity. This guide covers the storage requirements for Korean botulinum toxin products available through Korean Fillers EU.
Lyophilised Toxins (Botulax, Nabota, Liztox, Metox)
Pre-reconstitution storage: Store at -20°C for long-term storage. Most lyophilised Korean toxins have a shelf life of 2–3 years when stored correctly at -20°C. Refrigerated storage at 2–8°C is acceptable for short periods, typically up to 2–4 weeks, depending on the specific product.
Transport: Products should be transported with ice packs in insulated packaging. At Korean Fillers EU, all shipments include validated cold chain packaging to maintain appropriate temperatures during transit.
Vloeibaar Toxin (Innotox)
Critical difference: Innotox must be stored at 2–8°C and must NOT be frozen. The liquid formulation cannot withstand freezing. This is a key distinction from lyophilised products.
After Reconstitution (Lyophilised Products)
Once reconstituted, botulinum toxin solution should be kept at 2–8°C and used within 4–6 hours for optimal potency. Some studies support use up to 24 hours under refrigeration, but immediate use is recommended practice.
Never freeze reconstituted product. Refreezing can alter potency and introduce contaminants.
Clinic Storage Best Practices
- Designate a dedicated pharmaceutical refrigerator for toxin storage
- Monitor and log refrigerator/freezer temperatures daily
- Keep toxin away from the freezer door (temperature fluctuations)
- Never store toxin with food or non-pharmaceutical items